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- _6 wasQuotedFrom 11976320 provenance.
- _6 value "In support of previous findings, kinase-dead IRAK1 (K239A) transfection efficiently triggered κB luciferase activity at a level equivalent to that of wild type IRAK1, and this activity was similarly reduced by CaMKKc and Akt (Fig. 9C). These results suggest that the inhibition of IRAK1-dependent signaling by Akt is unrelated to the kinase activity of IRAK1." provenance.