Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA6KZiDvl2Uro1Wtxb1XMnvvHIZjpwRyo-HukVUXkLB_0#_7> ?p ?o ?g. }
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- _7 wasQuotedFrom 11713228 provenance.
- _7 value "We demonstrate that CIS produces a 70% inhibition of PRL signaling by a mechanism distinct from, and downstream of, the effect of SOCS-1 on JAK2. This inhibition involves association with the PRL receptor (PRLR), resulting in the inhibition of signal transducer and activator of transcription 5 (STAT5) activation. CIS binds the PRLR but inhibits signal transducer and activator of transcription 5 rather than JAK2." provenance.