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- _4 wasQuotedFrom 15833768 provenance.
- _4 value "we sought to assess whether TSP-1 is able to activate NF-?B. Using a NF-?B-dependent promoter construct, we monitored NF-?B activity after EC treatment with TSP-1 (Fig. 6A). We found that TSP-1 induced a threefold increase in promoter activity (normalized to control). In agreement with the literature (49), TNF-? provided a fivefold increase of NF-?B-dependent promoter activity." provenance.