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- _5 wasQuotedFrom 8327493 provenance.
- _5 value "Enzyme assays of PKC partially purified from transfected cells indicated at least a 5-fold increase in PKC activity upon expression of the wild-type protein or the NH2-terminal and hinge mutants. In contrast, no increased activity was detected upon expression of the COOH-terminal [Thr-634/Thr-641] mutant. ...the COOH-terminal autophosphorylation sites are critical for PKC function" provenance.