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- _4 wasQuotedFrom 17628011 provenance.
- _4 value "To address the effects of LXR signaling in human livers, we have used genome-wide expression profiling of primary human hepatocytes cultured at varying physiological concentrations of insulin and treated them with the synthetic LXR agonist GW3965. 85 genes were significantly upregulated and 105 genes were significantly downregulated by insulin and GW3965 treatment, respectively. 38 genes were significantly upregulated and 84 genes were significantly downregulated by insulin alone. Fold change was 1.5 increase or decrease compared to control." provenance.