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{ <http://www.tkuhn.ch/bel2nanopub/RAAd2N8YG3EwUeu5y5Rsve7o_iLkz-AC1eKTkOkohWu9Y#_5> ?p ?o ?g. }
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Based on these results, we conclude that SHP-2 is required for mediating PI3K/Akt activation, and the N-terminal SH2 domain is critically important for a \"positive\" role of SHP-2 in regulating PI3K pathway activation.
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