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- _3 wasQuotedFrom 12473186 provenance.
- _3 value "The molecular mechanism by which PKCh induces G1 arrest was demonstrated in our recent study. PKCh associates with the cyclin E/cdk2/p21 complex in the cytoplasm of normal human keratinocytes. This association results in the inhibition of cdk2 kinase activity, leading to the dephosphorylation of Rb proteins and thereby G1 arrest" provenance.