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- _3 wasQuotedFrom 11289656 provenance.
- _3 value "Treatment of Osteoarthritis (OA) synovial fibroblasts with 1 ng/ml IL-1beta dramatically increased IL-6. Addition of NS-398, a specific Cyclooxygenase (COX2) inhibitor completely blocked prostaglandin E2 (PGE2) production and partly suppressed IL-6 production, indicating that endogenous Prostaglandins mediate the production of IL-6 in response to IL-1beta." provenance.