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- _6 wasQuotedFrom 15777261 provenance.
- _6 value "Insulin and IGF-I initiate the biological effects in target cells by binding to and activating its endogenous tyrosine kinase receptors [23,24]. These receptors are believed to transduce signals by phosphorylation on tyrosine residues of several cellular substrates including IRS proteins (IRS-1,-2,- 3 and –4) [25-28]." provenance.