Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAEeKDwC28DS2N41lg-WIVSN8NtwWHm56-7stuIbHyVj4#_4> ?p ?o ?g. }
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- _4 wasQuotedFrom 15225548 provenance.
- _4 value "Using a stable SUZ12 knockdown cell line, we show SUZ12 knockdown results in cell growth defects, which correlate with genome-wide alteration on H3-K27 methylation as well as upregulation of a number of Hox genes. Chromatin immunoprecipitation (ChIP) assay identified a 500 bp region located 4 kb upstream of the HoxA9 transcription initiation site as a SUZ12 binding site, which responds to SUZ12 knockdown and might play an important role in regulating HoxA9 expression." provenance.