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{ <http://www.tkuhn.ch/bel2nanopub/RAF6R6wutwT6cB-zoLxT7UE42KhPXqQq7pJSXllf-fndo#_8> ?p ?o ?g. }
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In normal G1 progression, the Cyclin D1/CDK4 kinase phosphorylates RB, triggers disruption of the RB/ E2F complex, and frees E2F to activate genes that are necessary for S-phase progression.
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