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- _4 wasQuotedFrom 10843668 provenance.
- _4 value "Treatment of in vitro stimulated Peripheral blood lymphocytes (PBLs) with TNF alpha (30 ng/ml for 48 hours) showed a 10 fold increase in the chemokines namely MIP-1 alpha, MIP-1 beta, and RANTES. This up regulation was substantially decreased by NF kappa B-inhibitory peptide (KBI). Moreover treatment with KBI significantly weaker response on CCR5 expression, suggesting that NF kappa B signal is important for CCR5 down regulation induced by TNF alpha." provenance.