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- _4 wasQuotedFrom 10620335 provenance.
- _4 value "Although both ERα and AHR/ARNT specifically interact with the regulatory region of the c-fos gene, only E2 induced reporter activity from the FOS-1211 construct (Fig. 8B). The FOS-1211 oligomer binds ERa and AHR/ARNT in EMSA (data not shown). TCDD suppressed the E2-stimulated luciferase activity. COUP–TFI significantly inhibited E2-stimulated luciferase activity from FOS–1211, but had no effect in TCDD-treated cells." provenance.