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{ <http://www.tkuhn.ch/bel2nanopub/RAGJUJqe9d8P--iunwAHBE40P4EWhjYJ59waBnoox4LYM#_6> ?p ?o ?g. }
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"
S6K was shown to directly phosphorylate IRS-1 to inhibit phosphatidylinositol-3-kinase (PI3K) and Akt activation (Harrington ete al, 2004).
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