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- _4 wasQuotedFrom 12351404 provenance.
- _4 value "SOCS3 transformants and parental KT-1/A3R cells were incubated with 1000U of IFN-alpha for 30 minutes in which SOCS3 inhibited the IFN-alpha induced ISGF3 activation, suggesting that SOCS3 was an IFN-alpha inducible gene and that constitutive expression of SOCS3 conferred resistance to IFN-alpha in CML cell lines by bringing down the IFN-alpha induced activation of ISGF3." provenance.