Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAGq3HwWhs3MpNlNXwZXDxxz8qnFXrtr4QtryMn4w0rVI#_5> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _5 wasQuotedFrom 14710188 provenance.
- _5 value "In H4IIE hepatoma cells, D4476 specifically inhibits the phosphorylation of endogenous forkhead box transcription factor O1a (FOXO1a) on Ser322 and Ser325 within its MPD, without affecting the phosphorylation of other sites. Our results indicate that these residues are targeted by CK1 in vivo and that the CK1-mediated phosphorylation of the MPD is required for accelerated nuclear exclusion of FOXO1a in response to IGF-1 and insulin" provenance.