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- _4 wasQuotedFrom 12893815 provenance.
- _4 value "Data with IRAK-M knock-out mice have revealed that IRAK-M serves as a negative regulator of IL-1R/TLR signaling (19). IRAK-M-deficient macrophages produced significantly higher cytokine levels in response to a variety of IL-1R/TLR ligands." provenance.