Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAILLdGo1qatbwUiLBURyPFpNB9otj9arokPxj7-BLor4#_5> ?p ?o ?g. }
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- _5 wasQuotedFrom 14610084 provenance.
- _5 value "We show here that alpha5beta1 expression, and hence function, during angiogenesis is regulated by the transcription factor Hox D3, a homeobox gene that also controls the expression of endothelial cell integrin alphavbeta3 and urokinase-type plasminogen activator. Hox D3 expression in endothelial cells enhances integrin alpha5 protein and message expression, whereas Hox D3 antisense inhibits its expression. Hox D3 promotes alpha5 expression during angiogenesis in vivo, whereas inhibition of alpha5 expression by Hox D3 antisense suppresses angiogenesis." provenance.