Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAIy-18YjY5a6Hs48L6hAjGVrBLbXZp-veFVdx43NEDHU#_3> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 wasQuotedFrom 12810568 provenance.
- _3 value "The assembly of the TJ barrier was shown to associate with a significant plummeting in the levels of iNOS and eNOS, seemingly suggesting that their presence by producing NO might perturb TJ assembly. To further confirm the role of NOS on the TJ barrier function in vitro, zinc (II) protoporphyrin-IX (ZnPP), an NOS inhibitor and a soluble guanylate cyclase inhibitor, was added to the Sertoli cell cultures during TJ assembly. Indeed, ZnPP was found to facilitate the assembly and maintenance of the Sertoli cell TJ barrier, possibly by inducing the production of TJ-associated proteins, such as occludin. " provenance.