Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAL99kOR_0iM5EuhtAsZJE7GDE2sPA7Yz1d5Ah8TWrLCc#_5> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _5 wasQuotedFrom 15190072 provenance.
- _5 value "We show that the overactive FGFR2 S252W mutation induced decreased Src family kinase tyrosine phosphorylation and activity associated with decreased Lyn and Fyn protein expression in human osteoblasts. Thus, constitutive FGFR2 activation induces c-Cbl-dependent Lyn and Fyn proteasome degradation, resulting in reduced Lyn and Fyn kinase activity, increased ALP expression, and FGFR2 down-regulation." provenance.