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- _4 wasQuotedFrom 10433239 provenance.
- _4 value "xamination of the TGF{alpha} promoter sequence (Fig. 10Go) revealed the presence of both an octamer-like sequence between nt -610 and -603, and a downstream sequence between nt -596 and -587 similar to the TAATGARAT element in the HSV promoter, which has been shown to mediate inhibitory transcriptional effects of Oct-2 proteins (52, 63). Cotransfection of C6 cells with a reporter plasmid carrying a fragment of the TGF{alpha} promoter (-637 to +67) that contains both the octamer and the HSV-like motifs, and expression vectors containing either the Oct-2a or Oct-2c coding regions resulted in stimulation of the promoter’s activity (Fig. 10AGo). " provenance.