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- _4 wasQuotedFrom 15225871 provenance.
- _4 value "Stable transfection of NIH/3T3 fibroblasts with active Ras (H-RasV12) results in transformation and in significant intracellular ROS generation. The importance of intracellular ROS in RAS-mediated transformation is highlighted by the observation that pharmacological inhibition of the NADPH oxidase reverses transformation (Irani et al., 1997)." provenance.