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- _3 wasQuotedFrom 18391970 provenance.
- _3 value "FoxO and RUNX3, a Runt domain-containing transcription factor, interact and bind concomitantly to the promoter of BIM, a pro-apoptotic Bcl-2 family member, which contains one FoxO binding site and two RUNX3- binding domains in close proximity (Figure 5). FoxO and RUNX3 cooperate to upregulate this pro-apoptotic gene and consequently promote apoptosis in gastric cancer cells (Yamamura et al., 2006)." provenance.