Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RANfg-FPP_Jkc8DF-1RwZ1ddZohOUsBSRRgnVyD6bEcS8#_4> ?p ?o ?g. }
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- _4 wasQuotedFrom 15809062 provenance.
- _4 value "PTEN overexpression resulted in a significant decrease in the expression of IGF-I, -II, and IGF-IR. PTEN regulates IGFBP-3 at the transcriptional level PI3 kinase inhibitor, LY294002, upregulates IGFBP-3 expression but downregulates IGF-I and IGF-II, indicating that PTEN controls IGFBP-3 and IGFs by an Akt-dependent pathway." provenance.