Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAOXT3zPvS9pGD7e0U0JuE1dsHNUlLa25zMFZZspN4ckM#_7> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _7 wasQuotedFrom 15115658 provenance.
- _7 value "Platelet-derived growth factor (PDGF) has multiple functions including inhibition of apoptosis and promotion of cell proliferation. In this study, we show that Na(+)/H(+) exchanger regulatory factor 2 (NHERF2) binds to the carboxyl-terminal PDZ domain-binding motif of the PDGF receptor through a PDZ domain-mediated interaction, and evaluate the consequence on PDGF-induced proliferation. Stable transfection with NHERF2 increased the PDGF-induced phosphorylation of ERK and Akt in Rat1 embryonic fibroblasts." provenance.