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- _3 wasQuotedFrom 19768117 provenance.
- _3 value "To determine if NO activates JNK upstream of BAX and BAK, we treated Bax?/?/Bak?/? MEFs with DETA-NO and assessed JNK activity by measuring expression of phoshpo-cJun, a downstream target of JNK. NO activates JNK as early as 8 hours after exposure to NO, and this activation was sustained to 24 hours (Figure 6AFigure 6). " provenance.