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{ <http://www.tkuhn.ch/bel2nanopub/RAPHNmFPj4EGoT6okfcLjGFTvijGIPFXz1k4z4lq2UtgU#_4> ?p ?o ?g. }
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Up-regulation of p53 directly promotes Bax expression, which changes the integrity of mitochondria, leading to release of cytochrome c, activation of caspase-3 and eventually execution of apoptosis
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