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- _5 wasQuotedFrom 16731744 provenance.
- _5 value "Genes modulated only in response to the combined treatment with HGF and CDDP, but not by the single treatment, are particularly interesting as they could be better relatedtoHGF-mediated sensitization toCDDP. In fact, this is a distinctive response of ovarian cancer cells as shown in several ovarian cancer cell lines (8, 11). In this group, those above all down-modulated were PANK3, RAMP, RRM2, and TDG. Most of them have been already associated to cell proliferation and apoptosis and even to cancer cell resistance" provenance.