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- _5 wasQuotedFrom 15602009 provenance.
- _5 value "EGFR appear to play a key role in the regulation of mucus hypersecretion, with increased expression of mucin genes (MUC5AC, MUCB. EGFRs are activated by TGF-{alpha}, which is in turn activated by TACE activated via release of oxidants from cigarette smoke and neutrophils. TGF-{alpha} may also be activated by IL-13 and IL-9." provenance.