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- _4 wasQuotedFrom 10371521 provenance.
- _4 value "IFNB1 decreased mRNA expression of TNF-alpha and IFN-gamma. Protein levels of these two pro-inflammatory cytokines also were reduced in MS patients on treatment with IFNB1 when compared with normal subjects. TNF-alpha production increased after one year of therapy, reaching values similar to that of healthy controls but the IFN-gamma secretion continued to remain low." provenance.