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- _7 wasQuotedFrom 16404421 provenance.
- _7 value "The immunosuppressant rapamycin specifically inhibits mTOR activity and retards cancer growth. mTOR phosphorylates 4E-BP1 primarily at residues Ser65 abd Thr73. As a result, eIF4E is released from 4E-BP1 with a subsequent increase in cap-dependent translation (Mamane et al, 2004)." provenance.