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- _3 wasQuotedFrom 17855353 provenance.
- _3 value "We next examined the possible effects of anticancer drugs on the expression of Hsp70 and HspBP1 in tumor cells. All three anticancer drugs examined (vincristine, paclitaxel, and etoposide) induced a ~2.0 - 2.5-fold increase in the amount of HspBP1 in HeLa S3 cells (representative of tumor cells with a low HspBP1/Hsp70 molar ratio) as well as in MKN1 cells (representative of tumor cells with a high HspBP1/Hsp70 molar ratio), with the highest expression levels being apparent between 6 and 24 h after the onset of drug treatment (Fig. 5). In contrast, the expression level of Hsp70 was not substantially affected by exposure of the tumor cells to these anticancer drugs for up to 24 h." provenance.