Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAU-mpm18IS4EtAFK-7tx4UiT8VUncnLznwJuxGkr4XvA#_6> ?p ?o ?g. }
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- _6 wasQuotedFrom 14982927 provenance.
- _6 value "FSH-stimulated HIF-1 activity is inhibited by the PI 3-kinase inhibitor LY294002, the Rheb inhibitor FTI-277 (farnesyltransferase inhibitor-277), and the mTOR inhibitor rapamycin. These results show that FSH enhances HIF-1 activity downstream of the PI 3-kinase/AKT/Rheb/mTOR pathway in GCs and that HIF-1 activity is necessary for FSH to induce multiple follicular differentiation markers." provenance.