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- _6 wasQuotedFrom 16257959 provenance.
- _6 value "GSK-3beta phosphorylates MARK2 on Ser-212, one of the two reported phosphorylation sites (Thr-208 and Ser-212) found in the activation loop of MARK2. Down-regulation of either GSK-3beta or MARK2 by small interfering RNAs suppressed the level of phosphorylation on Ser-262. GSK-3beta is responsible for phosphorylating Ser-262 of tau through phosphorylation and activation of MARK2" provenance.