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- _3 value "from full text - Figure 2. Analysis of the senescence transriptome reveals significant overlap between cells undergoing RS and SIPS. A, microarray analysis of young BJ fibroblasts and BJ fibroblasts undergoing RS or bleomycin-induced SIPS. Hierarchical clustering of consistent transcript alterations across all conditions and replicas is plotted. B, Venn diagram plots genes that significantly overlap in fibroblasts undergoing RS and SIPS versus young. C, GO analysis of up-regulated classes in cells undergoing RS and SIPS compared with their younger counterparts (i.e., immune & inflammation, mitogens & regulation of proliferation, and extracellular matrix & secreted factors). " provenance.