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- _5 wasQuotedFrom 15057286 provenance.
- _5 value "First, BRCA1 is a target for phosphorylation by several of the protein serine/threonine kinases (for example, ATM, ATR and CHK2) that signal the presence of DNA breakage46, and its modification by these enzymes seems essential for further participation in mechanisms that enforce cell-cycle checkpoints that are triggered by DNA damage in the S and G2 phases of the cell cycle47-49." provenance.