Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAZ18EC4VMh9RyIC-zhvIUbrnBkG6ewcCVK2mO1CZESV8#_6> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _6 wasQuotedFrom 11861304 provenance.
- _6 value "Truncation of signal transducer and activator of transcription (STAT) 5 at the carboxy-terminal domain, either by genetic engineering or by proteolytic cleavage, results in generation of dominant-negative forms. Nuclear element is not necessary for calpain-mediated STAT5 cleavage, since this process occurs in platelets. We also found that STAT3 is a substrate for calpain in vivo and in vitro, indicating that calpain-mediated cleavage is a common feature of STAT3 and STAT5." provenance.