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- _3 wasQuotedFrom 16098831 provenance.
- _3 value "the Foxa2 gene was deleted quantitatively in the liver...Foxa1 mRNA expression was increased by about 70% PEPCK (phosphoenolpyruvate carboxykinase), the rate-limiting enzyme in gluconeogenesis; TAT (tyrosine aminotransferase), and IGFBP-1 (insulin growth factor binding protein 1). Concordant with previous findings, expression of all three genes is robustly induced by a prolonged fast in wild-type mice" provenance.