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- _4 wasQuotedFrom 17133101 provenance.
- _4 value "Thrombin also activates endothelial cells by cleaving and activating endothelial protease-activated receptors (PARs)-1 and 2, which increase inflammatory gene transcription [10,11] and stimulate expression of numerous leukocyte adhesion molecules including vascular cell adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), and E-selectin through nuclear factor-kB (NF-kB) and GATA-dependent transcription factor pathways [12,13]." provenance.