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{ <http://www.tkuhn.ch/bel2nanopub/RAgNxQetsMZc1nEDLy7zjJN9m3kyk-JHjT-uvlJfCE6Bc#_4> ?p ?o ?g. }
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Activation of Ca2+ release channels/ryanodine receptors (RyR) by the inward Ca2+ current (ICa) gives rise to Ca2+-induced Ca2+ release (CICR), the amplifying Ca2+ signaling mechanism that triggers contraction of the heart.
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