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- _5 wasQuotedFrom 16170185 provenance.
- _5 value "C-Raf activates other cellular effectors, but the extent of the interdependence of these actions on MEK1 and MEK2 is not clear. For example, C-Raf activation regulates cytoskeleton formation by modulating the polymerization status of vimentin.165 Cell survival signaling is also regulated by C-Raf, which induces phosphorylation of IkB in the NF-kB-Ik B complex." provenance.