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- _3 wasQuotedFrom 14715915 provenance.
- _3 value "increasing the levels of IGF1 within muscle cells by various in vivo and in vitro methods leads to increases in muscle mass due to an augmentation of muscle protein and DNA content the hypertrophic effects of IGF1 are attributed to both the activation of satellite cell to proliferate providing more myonuclei and to the \"true hypertrophy\" (ie increase cytoplasmic to DNA volume ratio) through increased protein synthesis within exisiting myofibers" provenance.