Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAi2vcqvzdIXJp1IHasBqltUVxQa6ue74--q0uOfxXNuM#_6> ?p ?o ?g. }
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- _6 wasQuotedFrom 11461907 provenance.
- _6 value "Schematic representation of NE-induced IL-8 signal transduction pathway in human bronchial epithelial cells. In bronchial epithelial cells, NE activates an as yet unidentified receptor. The cytosolic protein MyD88 acts as an adaptor coupling the receptor complex to IRAK. The signal is relayed downstream via TRAF-6 to the I?B kinases (IKKs) (via NIK/MEKK1), resulting in phosphorylation and degradation of I?B?, and subsequent release and translocation of NF?B to the nucleus where it transactivates IL-8 gene expression." provenance.