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- _6 wasQuotedFrom 16354586 provenance.
- _6 value "GRB7 also maps to 17q12 and has been shown to be overexpressed in some TGCTs [21,22]. GRB7 is an adapter molecule that can bind directly to KIT and ERBB2 through its SH2 domain [23] and is also proposed to bind directly to RAS through its RAS association domain. In this way, GRB7 may have an important role in the regulation of the downstream signaling of these kinases. Furthermore, GRB7 is also known to play a role in cell migration" provenance.