Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAjeoW3AwclyfCmUbLnHPZoDh7qJqZ23fdfYGwtyHI_vU#_5> ?p ?o ?g. }
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- _5 wasQuotedFrom 16950141 provenance.
- _5 value "Here, we show that IRE1alpha, an ER-resident protein kinase, has a crucial function in insulin biosynthesis. IRE1alpha phosphorylation is coupled to insulin biosynthesis in response to transient exposure to high glucose; inactivation of IRE1alpha signaling by siRNA or inhibition of IRE1alpha phosphorylation hinders insulin biosynthesis." provenance.