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{ <http://www.tkuhn.ch/bel2nanopub/RAkqkfZpYDdrf0POBKZwOwyuIXm9w0BaswDerUYbiU298#_5> ?p ?o ?g. }
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"
TNF-a appears to impair insulin signaling by increasing serine phosphorylation of IRS-1. Serine-phosphorylated IRS-1 inhibits insulin receptor tyrosine kinase activity, which leads to impaired downstream signaling
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