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{ <http://www.tkuhn.ch/bel2nanopub/RAkr-JRXuWwLD9helZJvQdgM1UpDrylvPYq4PMJay5D04#_6> ?p ?o ?g. }
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Loss of PTEN function leads to an elevated concentration of the PIP3 substrate, and consequent constitutive activation of downstream components of the PI3K pathway, including the AKT and mTOR kinases
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