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- _4 wasQuotedFrom 14641090 provenance.
- _4 value "Signals leading to NF- ?B activation activate the IKK complex, I-?Bs are phosphorylated, ubiquitinated and degraded. The released NF- ?B is transported into the nucleus and binds to gene control regions containing specific recognition sites. This system is maintained dynamically, that is even in the absence of signal I-?B–NF-?B complexes dissociate spontaneously [22,23]" provenance.