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- _4 wasQuotedFrom 14715858 provenance.
- _4 value "Caspase-8, caspase-7, and caspase-3 were involved in the induction of apoptosis (Fig. 5AGo), and this activity was observed within 1 h of TRAIL activation. In contrast, no activation of any caspase was detected in TECs not exposed to cytokines,. This supports that TRAIL signal transduction in TEC cells is blocked before caspase-8 activation. A gradual decrease in the concentration of full-length Bid in response to TRAIL is due to the cleavage of Bid by caspase-8 (Fig. 5AGo). " provenance.