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- _4 wasQuotedFrom 11978627 provenance.
- _4 value "Further, NF-kappaB is an obligatory mediator of most of these TNF-alpha responses....Absence of NF-kappaB activation (through overexpression on the inhibitor in the same cell) abolished suppression of >98% of the genes normally suppressed by TNF-alpha and induction of 60-70% of the genes normally induced by TNF-alpha" provenance.